DATA-ORIENTED DESIGN The hardware will thank you.
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Vectors in registers should be allowed to stay there.
Load Hit Store is never as annoying as when it makes your awesome vector based code suddenly fall apart. Subjecting a 4 element vector to a single element adjustment seems like such a small thing, hopefully this article by Jaymin Kessler will help you realise that you miss the cache so much that you cry yourself to sleep every night with a picture of it under your pillow.